The pandemic is disrupting every aspect of our health care system. Chelsea Dubie reflects on the need for a data and health IT infrastructure to address the who, what and how for these current unprecedented times and for the new reality that will follow. The COVID-19 (coronavirus disease 2019) pandemic has underscored the critical need for all countries to strengthen their health data and information systems and ensure the routes the data travel, from submission to use, are unobstructed. Timely, credible, reliable, and actionable data are key to ensuring that political decisions are data-driven and facilitate understanding, monitoring, and forecasting.